Croatian scientist dr. Nenad Bogdanović is Thon award winner

The world renowned Croatian scientist Dr. Nenad Bogdanović recently received the prestigious Norwegian Thon award worth of 10 million Norwegian crowns, in the competition of twenty scientific works.

Dr. Bogdanović was born in Zagreb in 1958, and in 1982 graduated from the Medical Faculty in Zagreb. Today is one of the most famous European neurogeriatrologists and neurosurgeons, head of the Swedish Biobank of brains, and an associate professor at the prestigious Karolinska Institute in the Stockholm, which is engaged in research of Alzheimer’s disease. In 2005 he received the so-called Little Nobel Prize – a prestigious award for his contribution in the scientific and educational work, award is provided by the Karolinska Institute, Dr. Bogdanović is the first foreigner who has received this award. Dr. Bogdanović is one of the members of the scientific team discovered that two mutations in the 21st chromosome (Swedish and Arctic mutations) that cause Alzheimer’s dementia. Throughout his career, Dr. Bogdanović is primarily devoted to the study of Alzheimer’s disease, and he gained world-wide reputation in this field of science.

Thon award Dr. Bogdanović received for his project in the area of early detection of Alzheimer’s disease. Dr. Bogdanović’s team from the Karolinska Institute intends during the four years of the project to develop a method of early diagnosis of Alzheimer’s disease through blood. This method aims to enable the diagnosis of Alzheimer’s disease while the patient has no signs of disease and no obvious memory problems. The procedure would be similar to the normal process of making blood count. By using modern techniques of fluorescent nanospectroscopy could detect the presence of only one molecule of pathological accumulation of amyloid in the blood serum and in the cerebral spinal fluid. The presence of pathological amyloid deposits is one of the earliest confirmation of Alzheimer’s disease. How would diagnose early signs of disease, developed in parallel with the development of drugs for Alzheimer’s disease, Dr. Bogdanović believes that this would enable faster development of drugs, and this would be a great help to monitor the effect of therapy, because it would be possible to determine that there are some improvements from consuming certain drugs. How would this method detect the disease early, It could also help with early beginning the elimination of the amyloid deposits in the brain, and thus to stop the development of Alzheimer’s disease.

 

Sources:

  1. http://www.sciencedirect.com/science/article/pii/S1552526016301418
  2. https://ots.olavthonstiftelser.no/en/
  3. http://content.iospress.com/articles/journal-of-alzheimers-disease/jad160461
  4. https://www.researchgate.net/profile/Nenad_Bogdanovic2
  5. https://tkojetko.irb.hr/znanstvenikDetalji.php?sifznan=9142&podaci=biografija
  6. http://www.alzheimer.hr/novosti/nenad-bogdanovi-vedska-karijera-borca-protiv-alzheimera/